Enzyme Engineering XXVIII

An ECI Conference Series

October 19-24, 2025
Marienlyst Strandhotel
Helsinger, Denmark

About This Conference

The Enzyme Engineering Conference is the leading international forum for discussion of enzyme engineering technology and applications. Enzyme Engineering XXVIII will be held in Helsingør, Denmark (October 19-24, 2025). This is only the second time the conference has been held in Denmark since the start of this conference series in 1971. Experts from around the world will present the latest research with the aim of stimulating discussion. Topics that will be discussed at the meeting will be of interest to experts in the field, as well as newcomers, and those that want to apply enzyme engineering in academic research and industrial practice.

Specific topics will include:

• Computational, AI tools and new technology for enzyme engineering
• Novel enzymes with non-natural amino acids, new metals, new cofactors
• Enzyme and chemo-enzymatic cascades
• Bioprocess engineering and scale-up of enzyme applications
• Enzymes in industrial applications
• Enzyme engineering for sustainability

Previous Conference Program [PDF]

Conference Organization

Jens Erik Nielsen
Novonesis, Denmark

Technical Liaison
Jeff Moore, Merck

Keynote Speakers

Industry Speakers

Codexis (USA)
Quantumzyme (India)
DSM-Firmenich (NL)
BioMatter (Lithuania)

Previous Enzyme Engineering Conferences

Enzyme Engineering
August 9-13, 1971
New England College, Henniker, New Hampshire
Conference Chair:
L.B. Wingard, Jr., SUNY Buffalo

Enzyme Engineering II
August 5-10, 1973
New England College, Henniker, New Hampshire
Conference Chairs:
L. B. Wingard, Jr., University of Pittsburgh
E. K. Pye, University of Pennsylvania

Enzyme Engineering III
August 3-8, 1975
Reed College, Portland, Oregon
Conference Chairs:
E. K. Pye, University of Pennsylvania
Howard H. Weetall, Corning Glass Works

Enzyme Engineering IV
September 25–30, 1977
Bad Neuenahr, W. Germany
Conference Chairs:
G. Manecke, der Freie Universität Berlin
L. B. Wingard, Jr., University of Pittsburgh

Enzyme Engineering V
July 29-August 3, 1979
New England College, Henniker, New Hampshire
Conference Chairs:
Howard H. Weetall, Corning Glass Works
G. P. Royer, University of Delaware

Enzyme Engineering VI
September 20-26, 1981
Kashikojima, Japan
Conference Chairs:
S. Fukui, Kyoto University
I. Chibata, Tanabe Seiyaku Co.

Enzyme Engineering VII
September 25-30, 1983
White Haven, Pennsylvania
Conference Chair:
Allen I. Laskin, Exxon Research & Eng. Co.

Enzyme Engineering VIII
September 22-27, 1985
Elsinor, Denmark
Conference Chair:
Klaus Mosbach, University of Lund

Enzyme Engineering IX
October 4-9, 1987
Santa Barbara, California
Conference Chairs:
Harvey W. Blanch, University of California, Berkeley
Alexander M. Klibanov, Massachusetts Institute of Technology

Enzyme Engineering X
September 24-29, 1989
Kashikojima, Japan
Conference Chair:
H. Okada, University of Osaka

Enzyme Engineering XI
September 22-27, 1991
Kona, Hawaii
Conference Chairs:
David A. Estell, Genencor
Douglas S. Clark, University of California, Berkeley

Enzyme Engineering XII
September 19-24, 1993
Deauville, France
Conference Chairs:
Daniel Thomas, University of Technology of Compiègne
Marie Dominique Legoy, University of Technology of Compiègne

Enzyme Engineering XIII
October 15-20, 1995
San Diego, California
Conference Chairs:
Jon Dordick, University of Iowa
Alan Russell, University of Pittsburgh

Enzyme Engineering XIV
October 12-17, 1997
Beijing, China
Conference Chairs:
Yao-Ting Yu, Nankai University
Gao-Xiang Li, Academia Sinica

Enzyme Engineering XV
October 10-15, 1999
Kailua-Kona, Hawaii
Conference Chairs:
David Anton, DuPont
Frances H. Arnold, California Institute of Technology
Robert Kelly, North Carolina State University

Enzyme Engineering XVI
October 7-12, 2001
Potsdam, Germany
Conference Chairs:
Frieder W. Scheller, University of Potsdam
Christian Wandrey, Research Center Jülich
Oreste Ghisalba, Novartis Pharma AG

Enzyme Engineering XVII
November 9-14, 2003
Santa Fe, New Mexico
Conference Chairs:
Stephen Benkovic, Pennsylvania State University
Chi-Huey Wong, Scripps Research Institute
Jeffrey Moore, Merck & Co., Inc.
Birgit Kosjek, Merck & Co., Inc.

Enzyme Engineering XVIII
October 9-14, 2005
Gyeong-ju, Korea
Conference Chairs:
Hak-Sung Kim, KAIST, Korea
Ji-Yong Song, LG Life Sciences, Ltd, Korea
Tae-Kwang Oh, Korea Research Inst.of Biosciences & Biotech, Korea
Moon-Hee Sung, Kookmin University, Korea

Enzyme Engineering XIX
September 23-28, 2007
British Columbia, Canada
Conference Chairs:
Romas Kazlauskas, University of Minnesota
Stefan Lutz, Emory University
David Estell, Danisco/Genencor

Enzyme Engineering XX
September 20-24, 2009
Groningen, the Netherlands
Conference Chairs:
Dick Janssen, University of Groningen
Oliver May, DSM Pharmaceutical Products
Andreas Bommarius, Georgia Institute of Technology

Enzyme Engineering XXI
September 18-22, 2011
Vail, Colorado
Conference Chairs:
Lori Giver, Codexis
Steve Withers, University of British Columbia

Enzyme Engineering XXII
September 22-26, 2013
Toyama, Japan
Conference Chairs:
Yasuhisa Asano, Toyama Prefectural University
Jun Ogawa, Kyoto University
Yoshihiko Yasohara, Keneka Corp.

Enzyme Engineering XXIII
September 6-11, 2015
St. Petersburg, Florida, USA
Conference Chairs:
Jon Dale Stewart, University of Florida
Robert DiCosimo, DuPont Industrial Biosciences

Enzyme Engineering XXIV
September 24-28, 2017
Toulouse, France
Conference Chairs:
Pierre Monsan, Toulouse White Biotechnology, France
Magali Remaud-Simeon, LISBP-INSA, University of Toulouse, France

Enzyme Engineering XXV
October 15-19, 2019
Whistler, British Columbia, Canada
Conference Chairs:
Huimin Zhao, University of Illinois at Urbana-Champaign, USA
John Wong, Pfizer, USA

Enzyme Engineering XXVI
May 22-27, 2022
Dallas/Fort Worth, Texas
Conference Chairs:
Andy Bommarius, Georgia Institute of Technology, USA
Vesna Mitchell, Codexis, USA
Doug Fuerst, GSK, USA

Enzyme Engineering XXVII
October 1-6, 2023
Singapore
Conference Chairs:
Ang Ee Lui, Singapore Institute of Food and Biotechnology Innovation. A*STAR
Yan Feng, Shanghair Giao Tong University, China
Li Zhi, National University of Singapore

General Information About ECI

Engineering Conferences International (ECI) is a not-for-profit, global engineering conferences program, originally established in 1962 that provides opportunities for the exploration of problems and issues of concern to engineers and scientists from many disciplines.

The format of the conference provides morning and late afternoon or evening sessions in which major presentations are made. Poster sessions will be scheduled for evening discussion as well. Available time is included during the afternoons for ad hoc meetings, informal discussions, and/or recreation. This format is designed to enhance rapport among participants and promote dialogue on the development of the meeting. We believe the conferences have been instrumental in generating ideas and disseminating information to a greater extent than is possible through more conventional forums.

All participants are expected both to attend the entire conference and to contribute actively to the discussions. The recording/photographing of lectures and presentations is forbidden. As ECI conferences take place in an informal atmosphere, casual clothing is the usual attire.

Smoking is prohibited at ECI conferences and conference functions.