Enzyme Engineering XXVIII

An ECI Conference Series

October 19-24, 2025
Marienlyst Strandhotel
Helsinger, Denmark

About This Conference

The Enzyme Engineering Conference is the leading international forum for discussion of enzyme engineering technology and applications. Enzyme Engineering XXVIII will be held in Helsingør, Denmark (October 19-24, 2025). This is only the second time the conference has been held in Denmark since the start of this conference series in 1971. Experts from around the world will present the latest research with the aim of stimulating discussion. Topics that will be discussed at the meeting will be of interest to experts in the field, as well as newcomers, and those that want to apply enzyme engineering in academic research and industrial practice.

Specific topics will include:

• Computational, AI tools and new technology for enzyme engineering
• Novel enzymes with non-natural amino acids, new metals, new cofactors
• Enzyme and chemo-enzymatic cascades
• Bioprocess engineering and scale-up of enzyme applications
• Enzymes in industrial applications
• Enzyme engineering for sustainability

Previous Conference Program [PDF]

Conference Organization

Technical Liaison:
Jeff Moore, Merck

Call for Abstracts

Please pick one or two topics from the list below that you feel your work fits best:

1. Computational, AI tools and new technology for enzyme engineering
2. Novel enzymes with non-natural amino acids, new metals, new cofactors
3. Enzyme and chemo-enzymatic cascades
4. Bioprocess engineering and scale-up of enzyme applications
5. Enzymes in industrial applications
6. Enzyme engineering for sustainability

Oral Abstract deadline: April 16, 2025

Poster Abstracts deadline:  May 15, 2025

All abstracts should be submitted electronically HERE.

• Please prepare your abstract according to this template: docx or doc.
• Only a limited number of oral presentation slots are available and thus all submissions for oral sessions will be considered for both oral and poster presentations.
• Abstracts of all presentations will be made available to conference participants prior to the start of the conference.

Poster size:  Your poster should be no larger than 1.5 meter high and 1.0 meter wide (Portrait Style)

Previous Enzyme Engineering Conferences

Enzyme Engineering
August 9-13, 1971
New England College, Henniker, New Hampshire
Conference Chair:
L.B. Wingard, Jr., SUNY Buffalo

Enzyme Engineering II
August 5-10, 1973
New England College, Henniker, New Hampshire
Conference Chairs:
L. B. Wingard, Jr., University of Pittsburgh
E. K. Pye, University of Pennsylvania

Enzyme Engineering III
August 3-8, 1975
Reed College, Portland, Oregon
Conference Chairs:
E. K. Pye, University of Pennsylvania
Howard H. Weetall, Corning Glass Works

Enzyme Engineering IV
September 25–30, 1977
Bad Neuenahr, W. Germany
Conference Chairs:
G. Manecke, der Freie Universität Berlin
L. B. Wingard, Jr., University of Pittsburgh

Enzyme Engineering V
July 29-August 3, 1979
New England College, Henniker, New Hampshire
Conference Chairs:
Howard H. Weetall, Corning Glass Works
G. P. Royer, University of Delaware

Enzyme Engineering VI
September 20-26, 1981
Kashikojima, Japan
Conference Chairs:
S. Fukui, Kyoto University
I. Chibata, Tanabe Seiyaku Co.

Enzyme Engineering VII
September 25-30, 1983
White Haven, Pennsylvania
Conference Chair:
Allen I. Laskin, Exxon Research & Eng. Co.

Enzyme Engineering VIII
September 22-27, 1985
Elsinor, Denmark
Conference Chair:
Klaus Mosbach, University of Lund

Enzyme Engineering IX
October 4-9, 1987
Santa Barbara, California
Conference Chairs:
Harvey W. Blanch, University of California, Berkeley
Alexander M. Klibanov, Massachusetts Institute of Technology

Enzyme Engineering X
September 24-29, 1989
Kashikojima, Japan
Conference Chair:
H. Okada, University of Osaka

Enzyme Engineering XI
September 22-27, 1991
Kona, Hawaii
Conference Chairs:
David A. Estell, Genencor
Douglas S. Clark, University of California, Berkeley

Enzyme Engineering XII
September 19-24, 1993
Deauville, France
Conference Chairs:
Daniel Thomas, University of Technology of Compiègne
Marie Dominique Legoy, University of Technology of Compiègne

Enzyme Engineering XIII
October 15-20, 1995
San Diego, California
Conference Chairs:
Jon Dordick, University of Iowa
Alan Russell, University of Pittsburgh

Enzyme Engineering XIV
October 12-17, 1997
Beijing, China
Conference Chairs:
Yao-Ting Yu, Nankai University
Gao-Xiang Li, Academia Sinica

Enzyme Engineering XV
October 10-15, 1999
Kailua-Kona, Hawaii
Conference Chairs:
David Anton, DuPont
Frances H. Arnold, California Institute of Technology
Robert Kelly, North Carolina State University

Enzyme Engineering XVI
October 7-12, 2001
Potsdam, Germany
Conference Chairs:
Frieder W. Scheller, University of Potsdam
Christian Wandrey, Research Center Jülich
Oreste Ghisalba, Novartis Pharma AG

Enzyme Engineering XVII
November 9-14, 2003
Santa Fe, New Mexico
Conference Chairs:
Stephen Benkovic, Pennsylvania State University
Chi-Huey Wong, Scripps Research Institute
Jeffrey Moore, Merck & Co., Inc.
Birgit Kosjek, Merck & Co., Inc.

Enzyme Engineering XVIII
October 9-14, 2005
Gyeong-ju, Korea
Conference Chairs:
Hak-Sung Kim, KAIST, Korea
Ji-Yong Song, LG Life Sciences, Ltd, Korea
Tae-Kwang Oh, Korea Research Inst.of Biosciences & Biotech, Korea
Moon-Hee Sung, Kookmin University, Korea

Enzyme Engineering XIX
September 23-28, 2007
British Columbia, Canada
Conference Chairs:
Romas Kazlauskas, University of Minnesota
Stefan Lutz, Emory University
David Estell, Danisco/Genencor

Enzyme Engineering XX
September 20-24, 2009
Groningen, the Netherlands
Conference Chairs:
Dick Janssen, University of Groningen
Oliver May, DSM Pharmaceutical Products
Andreas Bommarius, Georgia Institute of Technology

Enzyme Engineering XXI
September 18-22, 2011
Vail, Colorado
Conference Chairs:
Lori Giver, Codexis
Steve Withers, University of British Columbia

Enzyme Engineering XXII
September 22-26, 2013
Toyama, Japan
Conference Chairs:
Yasuhisa Asano, Toyama Prefectural University
Jun Ogawa, Kyoto University
Yoshihiko Yasohara, Keneka Corp.

Enzyme Engineering XXIII
September 6-11, 2015
St. Petersburg, Florida, USA
Conference Chairs:
Jon Dale Stewart, University of Florida
Robert DiCosimo, DuPont Industrial Biosciences

Enzyme Engineering XXIV
September 24-28, 2017
Toulouse, France
Conference Chairs:
Pierre Monsan, Toulouse White Biotechnology, France
Magali Remaud-Simeon, LISBP-INSA, University of Toulouse, France

Enzyme Engineering XXV
October 15-19, 2019
Whistler, British Columbia, Canada
Conference Chairs:
Huimin Zhao, University of Illinois at Urbana-Champaign, USA
John Wong, Pfizer, USA

Enzyme Engineering XXVI
May 22-27, 2022
Dallas/Fort Worth, Texas
Conference Chairs:
Andy Bommarius, Georgia Institute of Technology, USA
Vesna Mitchell, Codexis, USA
Doug Fuerst, GSK, USA

Enzyme Engineering XXVII
October 1-6, 2023
Singapore
Conference Chairs:
Ang Ee Lui, Singapore Institute of Food and Biotechnology Innovation. A*STAR
Yan Feng, Shanghair Giao Tong University, China
Li Zhi, National University of Singapore

Enzyme Engineering Award

The Award

A piece of Steuben glassware, appropriately engraved for the awardee from Genencor; a certificate, signed and dated by an officer of Engineering Conferences International (ECI), and a financial award of US$3,000 from ECI.

The award will be presented in the names of Engineering Conferences International and Genencor.

The Presentation

The 2025 Award will be presented by the Chairs of the 27th International Conference on Enzyme Engineering in October 2025 in Helsinger, Denmark. The awardee is to deliver an address during the conference, a requirement for acceptance.

Qualifications

The award is based on any or all of the following:

• New discoveries, research, process or device development or methodology relating to scientific or engineering achievements in the area of enzyme engineering.
• Outstanding contributions of a scientific or engineering nature in the design, operation or management of facilities, processes or devices based primarily on enzyme engineering.
• Distinguished service towards the development and growth of enzyme engineering.

Awardees may be from academic, governmental, industrial, or other organizations anywhere in the world and there are no age restrictions.

Nominations

Nominations are now being accepted.

They are to include:

One letter of nomination which is to include:

• Curriculum vitae (personal data, professional experience, list of publications and patents) of nominee.
• Record of contributions, with specific evidence of outstanding achievements.
• Paragraph citing the key factors on which the nomination is based.
• Two letters of recommendation.
• The complete nomination package should be submitted in an electronic form as a single PDF file with the name of the nominee, and should include the scanned, signed letters of support. This file is to be sent to Barbara@engconfintl.org.

No special forms are required; however, the packet must be complete at the time of submission. Questions should be submitted to Barbara Hickernell at Barbara@engconfintl.org with the subject line 2025 Enzyme Engineering Award Question.

Deadline

The deadline for receipt of completed nomination packets is April 30, 2025.

Selection

The Award Committee will review the nominations and recommend a candidate to the Executive Committee of the Enzyme Engineering Conference for approval.

The Executive Chair of the conference shall notify the nominee in advance of the conference, to ensure his or her willingness to accept the award, be present for its presentation and deliver the required address.

Enzyme Engineering Award – Past Recipients

1971–HENNIKER, NH, USA

1973–HENNIKER, NH, USA

1975–PORTLAND, OR, USA

1977–BAD NEUENAHR, GERMANY

1979–HENNIKER, NH, USA

1981–KASHIKOJIMA, JAPAN

1983–WHITE HAVEN, PA, USA — ICHIRO CHIBATA

1985–HELSINGOR, DENMARK — KLAUS MOSBACH

1987–SANTA BARBARA, CA, USA — EPHRIAM KATCHALSKI-KATZIR

1989–KASHIKOJIMA, JAPAN — SABURO FUKUI

1991–KONA, HAWAII, USA — ALEX KLIBANOV

1993–DEAUVILLE, FRANCE — MALCOLM LILLY

1995–SAN DIEGO, CA, USA — MARIA-REGINA KULA/ CHRISTIAN WANDREY

1997–BEIJING, CHINA — HARVEY BLANCH

1999–KONA, HAWAII, USA — CHI HUEY WONG

2001–POTSDAM, GERMANY — HIDEAKI YAMADA

2003–SANTA FE, NM, USA — JON DORDICK/DOUG CLARK

2005—GYEONG-JU, KOREA — DEWEY RYU

2007—HARRISON HOT SPRINGS, BC, CANADA — FRANCES H. ARNOLD

2009 – GRONINGEN, THE NETHERLANDS – SAKAYU SHIMIZU

2011 – VAIL, COLORADO, USA – DAVID ESTELL

2013 – TOYAMA, JAPAN – YASUHISA ASANO

2015 – ST. PETERSBURG, FLORIDA, USA – DAN TAWFIK

2017 – TOULOUSE, FRANCE – PIERRE MONSAN

2019 – WHISTLER, CANADA – HUIMIN ZHAO

2022 – DALLAS, TEXAS, USA – UWE BORNSCHEUER

2023 – SINGAPORE – HAK SUNG KIM

Conference Venue

Just one hour by train from Copenhagen, the coastal town of Helsingør (sometimes known in English as Elsinore) is located on Denmark’s North Riviera and is surrounded by golden beaches and forests. The town itself has many half-timbered houses and cobblestone streets that are lined with shops and restaurants.  As an 800-year-old market town, it has a unique maritime cultural history.

The town itself was founded by King Eric in the 1420s to tax foreign ships passing through the Oresund Strait.  In order to do that they needed a large castle which has become the town’s most famous landmark.  The Renaissance-style Kronborg Castle, known both for its beauty and its literary connection as the setting for Shakespeare’s Hamlet, is now a UNESCO World Heritage Site.  

It is, of course, open to visitors who come to admire its Renaissance architecture, castle grounds, and interior which include the castle chapel, tapestries, furnishings and crypts.  The view from the rooftop is stunning as one can see the Swedish town of Helsingborg, a 20-minute ferry ride away.

Besides the Kronberg Castle, visitors are drawn to the M/S Maritime Museum of Denmark, filled with interactive exhibitions. It is located on an old dry dock along the waterfront outside the Kronberg Castle.  The exhibits explore the topics of navigation, sailing, sea trade and naval warfare.  An unexpected exhibit explains the role that shipping and cargo freight play in today’s world.  The Danish Museum of Science and Technology is where you can find the world’s oldest working car from 1888 to a space capsule as well as the original LEGO from 1958 among other technological items.  The 16^th century St. Olaf’s Church is also worth a visit as it contains some ornate frescos.

The conference will take place at the Marienlyst Strandhotel (Ndr. Standvei 2, DK-3000 Helsingør).  The hotel is right on the beach and with the forest so close, it is in a very unique location with views over Oresund and Kronborg Castle.  It is a three-minute walk from the Marienlyst St. train station and 2 km from the Kronborg Castle.  The rooms offer free Wi-Fi, flat screen TVs and minibars.  The hotel has two restaurants, a bar, a yoga studio and a spa plus an indoor pool, a fitness center, and a casino with table games and slot machines.  Parking is free.

Transportation

Getting to Elsinore | VisitCopenhagen

General Information About ECI

Engineering Conferences International (ECI) is a not-for-profit, global engineering conferences program, originally established in 1962 that provides opportunities for the exploration of problems and issues of concern to engineers and scientists from many disciplines.

The format of the conference provides morning and late afternoon or evening sessions in which major presentations are made. Poster sessions will be scheduled for evening discussion as well. Available time is included during the afternoons for ad hoc meetings, informal discussions, and/or recreation. This format is designed to enhance rapport among participants and promote dialogue on the development of the meeting. We believe the conferences have been instrumental in generating ideas and disseminating information to a greater extent than is possible through more conventional forums.

All participants are expected both to attend the entire conference and to contribute actively to the discussions. The recording/photographing of lectures and presentations is forbidden. As ECI conferences take place in an informal atmosphere, casual clothing is the usual attire.

Smoking is prohibited at ECI conferences and conference functions.